Scintigraphic detection of peptic lesions with the method of radiolabelled sucralfate

نویسندگان

  • John Naumovski
  • Nina Simova
  • Emilija Janevik-Ivanovska
  • Elizabeta Kovkarova
  • Sonja Georgievska- Kuzmanovska
چکیده

Sucralfate, a complex polyaluminium hydroxide salt of polysulphated sucrose, is used in medical treatment of peptic disease as a coating agent that provides a protective barrier to further damage from acid and pepsin. Its actions are principally local and at acid pH becomes highly polar and binds by way of strong electrostatic interaction to ulcer tissue for up to 12 hours, while relatively little binds to intact gastric or duodenal mucosa.1 Radiol Oncol 2003; 37(1): 9-12.

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تاریخ انتشار 2003